Aafact 500 IU powder for solution for injection Each vial contains nominally 500 or 1000 International Units (IU) human coagulation factor VIII.Aafact contains approximately 100 IU/ml of human coagulation factor VIII after reconstitution.The potency (IU) is determined using the European Pharmacopoeia chromogenic assay. The specificactivity of Aafact is approximately 25 IU/mg protein.
Aafact is produced from the plasma of human donors.The 500 IU vial of this medicinal product contains1.2 mmol (27.6 mg) sodium per dose and the 1000IU vial contains 2.4 mmol (55.2 mg) sodium per dose. To be taken in consideration by patients on a controlled sodium diet.